Acetmainophen Effect on Prostaglandin E2; A Mechanism for Patent Ductus Arteriosus Closure
| Autor: | Perry V. Halushka, Carol L. Wagner, James Kiger, Shelly-Ann Williams, Matthew Halliday, John E. Baatz |
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| Rok vydání: | 2017 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities medicine.medical_specialty Side effect business.industry Ductus arteriosus closure Standard treatment Alternative treatment Acetaminophen medicine.anatomical_structure Anesthesia Ductus arteriosus Pediatrics Perinatology and Child Health medicine Neonatology Prostaglandin E2 business medicine.drug |
| Zdroj: | Section on Neonatal-Perinatal Medicine. |
| Popis: | The patent ductus arteriosus (PDA) has long been a treatment dilemma in the field of neonatology. Standard treatment regimens have considerable side effect profiles and surgical treatment carries significant risk to the neonate. Recent studies have demonstrated that acetaminophen may be a safe and effective alternative treatment to indomethacin for PDA closure. Currently, there are very few studies that have examined safety and pharmacologic mechanisms of acetaminophen in premature infants. We conducted a … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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