Cyclization of 5-alkynones with chromium alkylidene equivalents generated in situ from gem-dichromiomethanes
| Autor: | Takashi Kurogi, Masahito Murai, Kazuhiko Takai, Ryuji Taniguchi, Moritani Shunsuke |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
In situ Double bond Chemistry Metals and Alloys chemistry.chemical_element General Chemistry Medicinal chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Chromium chemistry.chemical_compound Nucleophile Electrophile Materials Chemistry Ceramics and Composites Alkyne metathesis Reactivity (chemistry) Carbene |
| Zdroj: | Chemical communications (Cambridge, England). 56(67) |
| ISSN: | 1364-548X |
| Popis: | A rare example of cyclization with 5-alkynones, which possess non-polar alkynyl and less electrophilic polar keto carbonyl groups, was demonstrated. The key to promoting carbene/alkyne metathesis followed by alkylidenation with pendant C[double bond, length as m-dash]O double bonds was the Schrock-type nucleophilic reactivity of the generated chromium carbene equivalents from readily available diiodomethanes and CrCl2 by simple heating. |
| Databáze: | OpenAIRE |
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