| Autor: |
Arielle C. Coughlin, Sofia Ahsanuddin, Dani Inglesby, Conner Fox, Hope Xu, Ilana Margulies, Farah Sayegh, Celine Soudant, Henry S. Sacks, Andrew Kaufman, Peter J. Taub |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Pediatric surgery international. 38(3) |
| ISSN: |
1437-9813 |
| Popis: |
The optimal age for minimally invasive repair of pectus excavatum (MIRPE) is unclear; this study investigates the differences in complication rates among different age groups undergoing repair.PubMed and Embase databases were searched from inception to October 2020. To assess age as a risk factor for complications, odds ratios from relevant studies were analyzed using the Mantel-Haenszel method with a random-effects model for younger vs older patients. Specific complication rates were compared between the two cohorts using a chi-squared test.Of the 4448 studies retrieved, 25 studies stratified complication data by age groups. From these studies, ten studies compared groups at ages 18 and ≥ 18 and four studies compared ages 20 and ≥ 20, and one study compared ages 19 and ≥ 19. These fifteen studies reported on 5978 patients, with 1188 complications, for a complication rate of 19.87%. Older patients were more likely to have complications in a pooled analysis of studies comparing older vs younger patients (OR = 1.66, 95% CI = 1.28-2.14, heterogeneity IIncreased age is a risk factor for complications of MIRPE. This supports repair of pectus excavatum prior to late adolescence. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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