Immunostimulant Effect of Egyptian Propolis in Rabbits
| Autor: | Hamdy Soufy, Somya A. Nassar, Amira H. Mohamed, Khaled M. A. Mahran, Soad M. Nasr |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
Veterinary medicine Pasteurella multocida vaccine Pasteurella multocida Article Subject medicine.drug_class animal diseases Pasteurella Infections lcsh:Medicine Immunostimulant lcsh:Technology Propolis General Biochemistry Genetics and Molecular Biology Microbiology Immune system Adjuvants Immunologic medicine otorhinolaryngologic diseases Animals Adverse effect lcsh:Science General Environmental Science biology lcsh:T lcsh:R General Medicine biology.organism_classification medicine.disease Inactivated vaccine lcsh:Q Rabbits Pasteurellosis Research Article |
| Zdroj: | The Scientific World Journal, Vol 2012 (2012) The Scientific World Journal |
| Popis: | The present experiment was conducted to study the effect of ethanolic extract of Egyptian propolis given alone or in combination with inactivatedPasteurella multocidavaccine on rabbits challenged with a virulent strain ofPasteurella multocida. Fifty-six New-Zealand rabbits, 6–8 weeks old and non-vaccinated against pasteurellosis, were randomly divided into eight equal groups. The first group was kept as a control for the experiment. The other groups received different treatments with propolis extract, inactivated vaccine, or both. The experiment continued for seven weeks during which clinical signs, body weight, and mortality rate were monitored, and blood samples were collected weekly for evaluating the leukogram, serum biochemistry, and immune response in all groups of animals. At the end of the seventh week, the animals were subjected to challenge with a virulent strain ofPasteurella multocida. Two weeks later, tissue specimens were collected from different organs for histopathological examination. Results showed that rabbits of the groups treated with both propolis and the vaccine by different routes appeared healthy after challenge. It has been concluded that alcoholic extract of propolis administrated in combination with inactivatedPasteurella multocidavaccine has no adverse effects on the general health conditions and enhances immune response in rabbits. |
| Databáze: | OpenAIRE |
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