Long-term follow-up of late morbidity, cosmetic outcome and body image after breast conserving therapy. A study from the Danish Breast Cancer Cooperative Group (DBCG)
| Autor: | Christina D Lyngholm, Jens Overgaard, Tine Engberg Damsgaard, Peer Christiansen |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Long term follow up medicine.medical_treatment Denmark Physical examination Breast Neoplasms Mastectomy Segmental Danish Breast cancer Internal medicine medicine Body Image Cooperative group Humans Radiology Nuclear Medicine and imaging Cooperative Behavior Societies Medical Aged Aged 80 and over Chemotherapy medicine.diagnostic_test business.industry Standard treatment Hematology General Medicine Middle Aged Plastic Surgery Procedures medicine.disease language.human_language Surgery Treatment Outcome Oncology language Female Morbidity business Mastectomy Follow-Up Studies |
| Zdroj: | Lyngholm, C D, Christiansen, P M, Damsgaard, T E & Overgaard, J 2013, ' Long-term follow-up of late morbidity, cosmetic outcome and body image after breast conserving therapy. A study from the Danish Breast Cancer Cooperative Group (DBCG) ', Acta Oncologica, vol. 52, no. 2, pp. 259-69 . https://doi.org/10.3109/0284186X.2012.744469 |
| ISSN: | 1651-226X |
| Popis: | The Danish Breast Cancer Cooperative Group (DBCG) introduced BCT as a standard treatment in Denmark in 1990. The aim of this study was to investigate late morbidity, cosmetic outcome, and body image after BCT and to associate these outcome variables with patient, tumor, and treatment characteristics. Material and methods. A total of 214 patients treated with BCT from 1989-2002 participated in a long-term follow-up visit comprising an interview, clinical examination, photos of the breast region and completion of a questionnaire on Body Image. Results. Median follow-up time was 12 years (range 7-20). Moderate to severe fibrosis was found in 23% of patients and was associated with chemotherapy [OR 2.6, CI (1.1; 5.9), p = 0.02], large breast size [OR 3.2, CI (1.6; 6.4), p = 0.001], and smoking [OR 2.4, CI (1.1; 4.9), p = 0.02]. Patients with a satisfactory cosmetic outcome, when assessed by a clinician, were characterized by small tumors [OR 3.2, CI (1.5; 6.8), p = 0.003] and small to medium sized breasts [OR 2.0, CI (1.1; 3.5), p = 0.002]. Fifty percent of patients scored good or excellent when assessed by a clinician compared to 88% when reported by the patients themselves. Patients satisfied with their own cosmetic outcome were the younger patients [ |
| Databáze: | OpenAIRE |
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