Calprotectin and Intestinal Fatty Acid Binding Protein (I-FABP) Level in Preterm Neonates with Necrotizing Enterocolitis
| Autor: | Satrio Wibowo, Ditya Arisanti, Soemarno Soemarno |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Urinary system Ischemia Inflammation Gastroenterology fluids and secretions I-FABP Necrotizing enterocolitis Internal medicine Medicine lcsh:Agriculture (General) Feces Calprotectin lcsh:R5-920 business.industry General Medicine Abdominal distension medicine.disease Preterm neonates lcsh:S1-972 digestive system diseases Intestinal Fatty Acid-Binding Protein lipids (amino acids peptides and proteins) medicine.symptom business lcsh:Medicine (General) |
| Zdroj: | Research Journal of Life Science, Vol 6, Iss 1, Pp 1-10 (2019) |
| ISSN: | 2355-9926 |
| Popis: | Necrotizing enterocolitis (NEC) is inflammatory state of intestinal tissue which mostly occurred in preterm neonates and associated with ischemia and inflammation. This study was aimed to investigate calprotectin level (inflammatory marker) and intestinal fatty acid binding protein (I-FABP) (ischemia marker) in preterm neonates with NEC. This research was designed as cross sectional which involve 32 preterm neonates divided into 2 groups as follows: NEC group (n=16 subjects) and control group (n=16 subjects). Diagnosis of NEC was established by clinical and radiological signs (abdominal distension and pneumatosis). Fecal calprotectin and urinary I-FABP were measured using ELISA method. Results showed that fecal calprotectin and urinary I-FABP was significantly higher in NEC group as compared to control group ( Mann-Whitney test , p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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