A surgical approach to Wilms’ tumour with retrohepatic vena caval extension
| Autor: | Timothy Rogers, Mohammad Bader, Suren G. Arul, Khaled Abdelaal |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Vena Cava Inferior Nephrectomy Wilms Tumor Inferior vena cava Pediatric surgery medicine Humans Neoplasm Invasiveness Thrombus Child Vein Retrospective Studies Thrombectomy Venous Thrombosis business.industry Wilms' tumor General Medicine Neoplastic Cells Circulating medicine.disease Kidney Neoplasms Surgery Dissection Venous thrombosis medicine.anatomical_structure Liver medicine.vein Chemotherapy Adjuvant Child Preschool Pediatrics Perinatology and Child Health cardiovascular system Female business |
| Zdroj: | Pediatric Surgery International. 29:229-232 |
| ISSN: | 1437-9813 0179-0358 |
| DOI: | 10.1007/s00383-013-3263-2 |
| Popis: | Wilms’ tumours (WT) with retrohepatic vascular extension traditionally requires cardiac bypass for complete excision. We share our experience of these complex cases. A retrospective review was performed of children with WT with retrohepatic vascular extension presenting to two UK children’s hospitals. Tumour stage, chemotherapy, level of vascular extension, operative details and complication data were analysed. Ten children were identified. Mean age 6.6 years (range 3.3–8.2 years); tumour side 6 right, 2 left, 2 bilateral. Level of tumour extension was to the right atrium in two, diaphragm in two, hepatic vein (HV) level in four and retrohepatic inferior vena cava (IVC) in one patient. Following chemotherapy it reduced to hepatic veins (5) or below (4). Surgery involved radical nephrectomy and complete mobilisation of the liver off the IVC, which was then clamped, opened and the thrombus excised. There were no intraoperative complications. Mean hospital stay was 9.77 days (7–20 days). Histology showed viable tumour thrombus in six patients. One patient died after 1 year from metastatic disease. Retrohepatic extension of WT can be managed without bypass using pre-operative chemotherapy and by complete liver mobilisation. The tumour was always adherent to IVC and required sharp dissection. |
| Databáze: | OpenAIRE |
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