Postpandemic Influenza Mortality of Venovenous Extracorporeal Membrane Oxygenation–Treated Patients in Reunion Island: A Retrospective Single Center Study
| Autor: | David Vandroux, Julien Jabot, Jérôme Allyn, Hugo Kerambrun, Cyril Ferdynus, Bernard-Alex Gaüzère, Nicolas Allou, Olivier Martinet |
|---|---|
| Přispěvatelé: | Neuroépidémiologie Tropicale (NET), Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie [CHU Limoges], CHU Limoges, Centre hospitalier Félix-Guyon [Saint-Denis, La Réunion], Centre de Médecine Tropicale René Labusquière |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment postpandemic 030204 cardiovascular system & hematology Single Center law.invention Cohort Studies 03 medical and health sciences 0302 clinical medicine Extracorporeal Membrane Oxygenation 030202 anesthesiology law Internal medicine Influenza Human venovenous ECMO Extracorporeal membrane oxygenation medicine Humans Retrospective Studies business.industry Reunion Island France Mortality rate Incidence (epidemiology) Intensive care unit Confidence interval Influenza 3. Good health Anesthesiology and Pain Medicine Standardized mortality ratio surgical procedures operative ICU [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie France ECMO Cardiology and Cardiovascular Medicine business Reunion Cohort study |
| Zdroj: | Journal of Cardiothoracic and Vascular Anesthesia Journal of Cardiothoracic and Vascular Anesthesia, WB Saunders, 2020, 34 (6), pp.1426-1430. ⟨10.1053/j.jvca.2019.12.043⟩ |
| ISSN: | 1053-0770 |
| DOI: | 10.1053/j.jvca.2019.12.043⟩ |
| Popis: | Objectives: The aim of the present study was to assess the post-pandemic mortality of influenza in patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO) in Reunion Island, France, by comparing the incidence with other patients undergoing VV-ECMO. Design: Retrospective, descriptive, and single-center cohort study. The primary outcome was the standardized mortality ratio for influenza based on the quartiles of the Respiratory Extracorporeal Membrane Oxygenation Survival Prediction score (RESP Score) in the reference population of patients undergoing VV-ECMO. Setting: Intensive care unit (ICU), Felix Guyon Hospital, University Teaching Hospital of La Reunion, La Reunion, France. Participants: Consecutive patients on ECMO with positive polymerase chain reaction for influenza. Interventions: None. Measurements and main results: One hundred twenty-seven consecutive patients were hospitalized in the ICU with a positive influenza polymerase chain reaction from January 2013 to December 2017. Twenty-four influenza patients underwent ECMO including 18 patients with VV-ECMO. During this period, 72 patients requiring VV-ECMO were hospitalized in the ICU. The overall mortality rate of influenza patients on VV-ECMO was 61% versus 46% for non-influenza patients. The standardized mortality ratio per quartile of RESP Score was 1.28 (95% confidence interval 0.61-2.35). Conclusions: In Reunion, the mortality of patients undergoing VV-ECMO for severe influenza is not lower than the expected mortality of all patients undergoing VV-ECMO. |
| Databáze: | OpenAIRE |
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