B cell depletion and pregnancy: Review and applications for MS treatment
| Autor: | Christopher Eckstein, Suma Shah |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Chronic condition
Pediatrics medicine.medical_specialty Multiple Sclerosis Pregnancy review Primary progressive 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans Immunologic Factors 030212 general & internal medicine Young adult Disease management (health) B-Lymphocytes business.industry Multiple sclerosis General Medicine medicine.disease Pregnancy Complications B cell depletion Neurology Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Multiple Sclerosis and Related Disorders. 33:153-157 |
| ISSN: | 2211-0348 |
| DOI: | 10.1016/j.msard.2019.06.003 |
| Popis: | Multiple sclerosis (MS) is a chronic autoimmune condition primarily affecting young adults. As there are numerous uncertainties faced by young women of childbearing age who are living with this chronic condition and the gender ratio is increasingly skewed towards women, it has become critical to define a clear approach to questions of disease management prior to and during pregnancy. With the approval of B cell depletion therapy for treatment of relapsing remitting and primary progressive MS, we explore the available data on using this type of therapy in the setting of pregnancy. We also provide recommendations regarding use of B-cell depleting therapies for patients who are considering or attempting conception. |
| Databáze: | OpenAIRE |
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