Somatostatin Analogs in Clinical Practice: A Review
| Autor: | Jersy Cardenas-Salas, Mariana Gomes-Porras, Cristina Álvarez-Escolá |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
carcinoid
Octreotide pituitary adenoma Review Neuroendocrine tumors Lanreotide Gastroenterology lcsh:Chemistry Somatostatin analog chemistry.chemical_compound 0302 clinical medicine lcsh:QH301-705.5 Spectroscopy General Medicine Diabetic retinopathy Computer Science Applications Neuroendocrine Tumors Somatostatin 030220 oncology & carcinogenesis Dumping syndrome lanreotide neuroendocrine tumor medicine.drug medicine.medical_specialty Antineoplastic Agents Hormonal 030209 endocrinology & metabolism Macular Edema Catalysis Inorganic Chemistry 03 medical and health sciences Stomach Neoplasms Internal medicine Intestinal Neoplasms medicine Humans cancer Pituitary Neoplasms Physical and Theoretical Chemistry Molecular Biology pasireotide Diabetic Retinopathy business.industry Organic Chemistry medicine.disease Pasireotide Graves Ophthalmopathy Pancreatic Neoplasms lcsh:Biology (General) lcsh:QD1-999 chemistry Congenital hyperinsulinism Growth Hormone-Secreting Pituitary Adenoma business octreotide |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 21, Iss 5, p 1682 (2020) |
| ISSN: | 1422-0067 |
| DOI: | 10.3390/ijms21051682 |
| Popis: | Somatostatin analogs are an invaluable therapeutic option in the diagnosis and treatment of somatotropinomas, thyrotropinomas, and functioning and non-functioning gastroenteropancreatic neuroendocrine tumors. They should also be considered an effective and safe therapeutic alternative to corticotropinomas, gonadotropinomas, and prolactinomas resistant to dopamine agonists. Somatostatin analogs have also shown to be useful in the treatment of other endocrine diseases (congenital hyperinsulinism, Graves’ orbitopathy, diabetic retinopathy, diabetic macular edema), non-endocrine tumors (breast, colon, prostate, lung, and hepatocellular), and digestive diseases (chronic refractory diarrhea, hepatorenal polycystosis, gastrointestinal hemorrhage, dumping syndrome, and intestinal fistula). |
| Databáze: | OpenAIRE |
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