Application of Controlled Hydrogen-ion Concentration for Antiseptic Use
| Autor: | Benjamin P. Hecht, Edwin J. Fredenburgh |
|---|---|
| Rok vydání: | 1951 |
| Předmět: |
chemistry.chemical_classification
Hydrogen ion Hydrogen Base (chemistry) medicine.drug_class Antibiotics chemistry.chemical_element Pathogenic bacteria Antibacterial effect Hydrogen-Ion Concentration medicine.disease_cause chemistry Antiseptic Biochemistry Anti-Infective Agents Local medicine Potency Nuclear chemistry |
| Zdroj: | Journal of the American Pharmaceutical Association (Scientific ed.). 40:126-131 |
| ISSN: | 0095-9553 |
| DOI: | 10.1002/jps.3030400304 |
| Popis: | A hydrogen-ion concentration corresponding to pH 3.5 is shown to exhibit bactericidal to bacteriostatic properties toward pathogenic bacteria. This hydrogen-ion concentration is found to be safe for use in topical aplication. Greater antibacterial effect is demonstrated by using a buffer to maintain tge pH. The composition of the buffer system is described in regard to base and acid components. The antiseptic potency of hydrogen ions is compared with the antibiotics and several other antibacterial agents. |
| Databáze: | OpenAIRE |
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