Effect of dialysis and ultrafiltration on osmolality, colloid osmotic pressure, and vascular refilling rate
| Autor: | Francisco Llach, Mariano Rodriguez, James A. Pederson |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Adult
Oncotic pressure medicine.medical_specialty medicine.medical_treatment Urology Ultrafiltration Osmolar Concentration Osmotic Pressure Renal Dialysis medicine Humans Osmotic pressure Plasma Volume Osmotic concentration Chemistry Blood Proteins Middle Aged Surgery Plasma osmolality Blood Nephrology Blood Vessels Hemodialysis Dialysis (biochemistry) |
| Zdroj: | Kidney International. (5):808-813 |
| ISSN: | 0085-2538 |
| DOI: | 10.1038/ki.1985.202 |
| Popis: | Effect of dialysis and ultrafiltration on osmolality, colloid osmotic pressure, and vascular refilling rate. The effect ofregular dialysis and isolated ultrafiltration on plasma osmolality, plasma colloid osmotic pressure (COP), plasma volume, and vascular refilling rate was evaluated in maintenance dialysis patients. Nineteen patients underwentregular dialysis and 11 isolated ultrafiltration. Blood samples from these subjects were obtained from arterial or venous dialysis system ports and peripheral veins. For any decrease in plasma volume, there was an increment in COP with each procedure in both venous and arterial ports and the presence of a progressive decrease of plasma osmolality was observed only during regular dialysis. Second, five additional patients underwent 2hrs of regular dialysis and isolated ultrafiltration in separate sessions removing comparable amounts of fluid (∼ 2.5 liter); after 2 hrs, there were no differences in the changes of plasma volume and COP, but again plasma osmolality decreased only during regular dialysis. These studies demonstrate that moderatechanges in plasma osmolality do not affect COP. Furthermore, the ability ofthe plasma to recruit fluid and generate vascular refilling (as assessed by COP) is similar during regular dialysis and isolated ultrafiltration, provided the rates of ultrafiltration are the same. |
| Databáze: | OpenAIRE |
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