Antiviral activity of carrageenans and processing implications
| Autor: | Herminia Domínguez, María Dolores Torres, Milena Álvarez-Viñas, Isabel Bandín, Noelia Flórez-Fernández, Sandra Souto |
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| Rok vydání: | 2021 |
| Předmět: |
Aquatic Organisms
QH301-705.5 Pharmaceutical Science 2510.04 Botánica Marina Review Carrageenan Antiviral Agents 01 natural sciences sulfated polysaccharides 03 medical and health sciences chemistry.chemical_compound Sulfation Biological property Drug Discovery Humans depolymerization 3390.01 Biotecnología de Microalgas Biology (General) Pharmacology Toxicology and Pharmaceutics (miscellaneous) 030304 developmental biology 0303 health sciences 010405 organic chemistry Chemistry Seaweed Combinatorial chemistry 0104 chemical sciences Drug delivery extraction 3209 Farmacología Sulfated polysaccharides red seaweed Phytotherapy |
| Zdroj: | Investigo. Repositorio Institucional de la Universidade de Vigo Universidade de Vigo (UVigo) Marine Drugs, Vol 19, Iss 437, p 437 (2021) Marine Drugs |
| Popis: | Carrageenan and carrageenan oligosaccharides are red seaweed sulfated carbohydrates with well-known antiviral properties, mainly through the blocking of the viral attachment stage. They also exhibit other interesting biological properties and can be used to prepare different drug delivery systems for controlled administration. The most active forms are λ-, ι-, and κ-carrageenans, the degree and sulfation position being determined in their properties. They can be obtained from sustainable worldwide available resources and the influence of manufacturing on composition, structure, and antiviral properties should be considered. This review presents a survey of the antiviral properties of carrageenan in relation to the processing conditions, particularly those assisted by intensification technologies during the extraction stage, and discusses the possibility of further chemical modifications. Xunta de Galicia | Ref. ED431G2019/06 Xunta de Galicia | Ref. ED481B-2018/002 Xunta de Galicia | Ref. ED481B-2018/071 Xunta de Galicia | Ref. ED431F 2020/01 Agencia Estatal de Investigación | Ref. RTI2018-096376-B-I00 Ministerio de Ciencia, Innovación y Universidades (España) | Ref. RYC2018-024454-I |
| Databáze: | OpenAIRE |
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