Relationship between Hepatitis B Viral Deoxyribonucleic Acid Load and Hepatocellular Carcinoma
| Autor: | Nooruddin Ahmed, Salimur Rahman, Mobin Khan, Mamun Al Mahtab, Shahidul Islam, Muhammad M Hussain |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Hepatocellular carcinoma medicine.disease_cause Fine needle aspiration cytology Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Hepatitis b viral Hepatitis B virus Alpha fetoprotein business.industry Brief Report Hepatology Hepatitis B medicine.disease digestive system diseases Ultrasonography Hepatitis B surface antigen chemistry 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Hepatitis B virus deoxyribonucleic acid (polymerase chain reaction) Alpha-fetoprotein business Viral load DNA |
| Zdroj: | Euroasian Journal of Hepato-Gastroenterology |
| ISSN: | 2231-5128 2231-5047 |
| DOI: | 10.5005/jp-journals-10018-1228 |
| Popis: | Introduction Hepatitis B virus (HBV) infection is an established cause of hepatocellular carcinoma (HCC) and is associated with poor prognosis. High HBV deoxyribonucleic acid (DNA) load has been identified in HCC and hepatitis B surface antigen-positive patients. Materials and methods This study was done in the Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, from January 2006 to December 2007. Thirty patients with HBV infection-related HCC were enrolled. Another 30 patients with HBV-related liver diseases without HCC were analyzed as controls. Results The HCC patients had a high viral load (>105 copies/mL), while all of the controls had low (5 copies/mL) viral load. Conclusion It seems that patients with HCC bear high HBV DNA loads in Bangladesh, but the causes underlying this remain to be resolved. How to cite this article Hussain MM, Al Mahtab M, Islam S, Ahmed N, Rahman S, Khan M. Relationship between Hepatitis B Viral Deoxyribonucleic Acid Load and Hepatocellular Carcinoma. Euroasian J Hepato-Gastroenterol 2017;7(1):111-112. |
| Databáze: | OpenAIRE |
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