Long term chemoradiotherapy-related dental and skeletal complications in a young female with nasopharyngeal carcinoma
| Autor: | Christos Papaloukas, Ioulia Ioannidou-Marathiotou, Nikolaos Eleftheriadis, Kyriaki Pistevou-Gompaki |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
lcsh:R5-920
business.industry medicine.medical_treatment nasopharyngeal carcinoma Mandible Dentistry Case Report General Medicine medicine.disease Radiation therapy stomatognathic diseases Nasopharyngeal carcinoma medicine Posterior teeth adolescence business Young female Radiation treatment planning lcsh:Medicine (General) dental and skeletal complications Chemoradiotherapy Anterior teeth radiotherapy |
| Zdroj: | International Journal of General Medicine, Vol 2010, Iss default, Pp 187-196 (2010) International Journal of General Medicine |
| ISSN: | 1178-7074 |
| Popis: | Ioulia Ioannidou-Marathiotou1, Kyriaki Pistevou-Gompaki2, Nikolaos Eleftheriadis3, Christos Papaloukas41Department of Orthodontics, School of Dentistry, Aristotle University of Thessaloniki, 2Department of Radiation Oncology, AHEPA University Hospital, Aristotle University of Thessaloniki, 3Propaedeutic Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, 4Department of Radiation Oncology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, GreeceAbstract: We describe the long-term complications six years after chemoradiotherapy in a 20-year old woman with nasopharyngeal carcinoma. We wanted to know whether the radiation dose was constant throughout the oral cavity, and thus uniformly affecting the corresponding dental and skeletal structures. Clinical and radiologic findings are described six years after chemoradiotherapy based on a two-dimensional computerized treatment planning system. This revealed radiation caries limited only to posterior teeth, proximal caries in the anterior teeth, limited but continuous salivary flow, mild periodontal infection, mild xerostomia, and a regenerative capacity of bones and the developmental process. The quantitative assessment of radiation delivered to the mandible revealed a high radiation dose in the posterior area and a minimal dose in the anterior area. This explains the differences in caries manifestation between the anterior and posterior teeth. According to the present study, individualized radiation fields, using a two-dimensional treatment planning system, result in restriction of severe damage of the dental and skeletal structures, which usually follows chemoradiotherapy. Orthodontic treatment could be initiated according to individual patient needs.Keywords: nasopharyngeal carcinoma, adolescence, radiotherapy, dental and skeletal complications |
| Databáze: | OpenAIRE |
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