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Savytskyi I. V., Znamerovskyi S. G., Koshelnik O. L., Miastkivska I. V., Grigoriev P. E., Yakimchuk N. V. Dynamics of blood indicators as a marker of the grain of the grease peritonitis. Journal of Education, Health and Sport. 2017;7(7):1027-1041. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1000944 http://ojs.ukw.edu.pl/index.php/johs/article/view/4952 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 01.07.2017. Revised: 02.07.2017. Accepted: 31.07.2017. DYNAMICS OF BLOOD INDICATORS AS A MARKER OF THE GRAIN OF THE GREASE PERITONITIS I. V. Savytskyi1, S. G. Znamerovskyi2, O. L. Koshelnik1, I. V. Miastkivska1, P. E. Grigoriev3, N. V. Yakimchuk1 1Odesa National Medical University, Odesa, Ukraine 2Ukrainian Scientific Research Institute of Medicine of Transport, Odesa, Ukraine 3Tyumen State University, Tyumen, Russia Abstract Introduction. Bile peritonitis is one of the most serious diseases of the abdominal cavity. The severity of its course and the percentage of mortality is primarily depends on endogenous intoxication. Therefore, effective sanitation of the abdominal cavity is an important element of the complex treatment of this pathology. Goal. Study of the dynamics of hematological parameters in the development of experimental bile peritonitis. Materials and methods of research. The investigation was carried out on 180 rats of the Wistar line with a mass 180-200 grams. Animals were divided into 4 groups: 1 group - intact (20 animals); 2 group - control - rats, that were modeled bile peritonitis without further correction (80 animals); Group 3 - animals whose modeled bile peritonitis was corrected by ablation of the abdominal cavity with a solution of furacilin and standard antibiotic therapy (40 animals); 4 group - rats, whose modeled bile peritonitis was corrected according to the combined scheme of detoxification. The task of this work is to investigate the dynamics of the indicators on the 1st, 3rd and 7th days. Results. The choice of erythrocyte, hemoglobin, hematocrit, ESR, leukocyte and leukocyte index of intoxication is optimal for the analysis of pathophysiological aspects of experimental bile peritonitis. Very high differences (p Differences between the indices on the 1st, 3rd and 7th days at the level of statistical significance p Conclusions. Conducting blood sampling on the 1st, 3rd and 7th day with the conditions of our experiment allows us to fully reveal the features of the flow of experimental bile peritonitis, as well as the influence of the methods of its correction in dynamics. Key words: biliary peritonitis, model, abdominal sanitation, erythrocytes, hemoglobin, hematocrit, ESR, leukocytes, leukocyte intoxication index. |
