Is Hypoalbuminemia an Independent Prognostic Factor in Patients with Gastric Cancer?
| Autor: | Robert C. Stuart, Donald C. McMillan, Margaret McKernan, Andrew B. C. Crumley |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Gastroenterology Predictive Value of Tests Stomach Neoplasms Albumins Internal medicine medicine Humans Hypoalbuminemia Stomach cancer Survival analysis Aged Univariate analysis business.industry Metabolic disorder Albumin Cancer Middle Aged Prognosis medicine.disease Survival Analysis Systemic Inflammatory Response Syndrome Surgery C-Reactive Protein Predictive value of tests Female business |
| Zdroj: | World Journal of Surgery. 34:2393-2398 |
| ISSN: | 1432-2323 0364-2313 |
| Popis: | Studies have indicated that hypoalbuminemia is associated with decreased survival of patients with gastric cancer. However, the prognostic value of albumin may be secondary to an ongoing systemic inflammatory response. The aim of the study was to assess the relation between hypoalbuminemia, the systemic inflammatory response, and survival in patients with gastric cancer. Patients diagnosed with gastric carcinoma attending the upper gastrointestinal surgical unit in the Royal Infirmary, Glasgow between April 1997 and December 2005 and who had a pretreatment measurement of albumin and C-reactive protein (CRP) were studied. Most of the patients had stage III/IV disease and received palliative treatment. The minimum follow-up was 15 months. During follow-up, 157 (72%) patients died of their cancer. On univariate analysis, stage (p |
| Databáze: | OpenAIRE |
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