Anthelmintic Resistance of Strongyle Nematodes to Ivermectin and Fenbendazole on Cart Horses in Gondar, Northwest Ethiopia
| Autor: | Zewdu Seyoum, Basazinew Bogale, Shimelis Dagnachew, Alemu Zewdu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Cart Veterinary medicine Article Subject Drug Resistance lcsh:Medicine Strongyle Infections Equine Drug resistance Biology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Ivermectin parasitic diseases medicine Animals Horses Anthelmintic Feces General Immunology and Microbiology lcsh:R Horse General Medicine 030108 mycology & parasitology Strongylus Fenbendazole Ethiopia After treatment Research Article medicine.drug |
| Zdroj: | BioMed Research International, Vol 2017 (2017) BioMed Research International |
| ISSN: | 2314-6141 2314-6133 |
| DOI: | 10.1155/2017/5163968 |
| Popis: | A study was conducted from November 2015 to April 2016 to determine fenbendazole and ivermectin resistance status of intestinal nematodes of cart horses in Gondar, Northwest Ethiopia. Forty-five strongyle infected animals were used for this study. The animals were randomly allocated into three groups (15 horses per group). Group I was treated with fenbendazole and Group II with ivermectin and Group III was left untreated. Faecal samples were collected from each cart horse before and after treatment. Accordingly, the reduction in the mean fecal egg count at fourteen days of treatment for ivermectin and fenbendazole was 97.25% and 79.4%, respectively. It was significantly different in net egg count between treatment and control groups after treatment. From the study, resistance level was determined for fenbendazole and suspected for ivermectin. In addition, a questionnaire survey was also conducted on 90 selected cart owners to assess their perception on anthelmintics. In the survey, the most available drugs in the study area used by the owners were fenbendazole and ivermectin. Most respondents have no knowledge about drug management techniques. Hence, animal health extension services to create awareness regarding anthelmintic management that plays a key role in reducing the anthelmintic resistance parasites. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|