Single-lung transplantation in a patient with cystic fibrosis and an asymmetric thorax

Autor: Terence J. Donovan, Hans R. Zerkowski, Felix Ratjen, Fred Splittgerber, Jarowit Piotrowski
Rok vydání: 1997
Předmět:
Zdroj: The Annals of thoracic surgery. 64(5)
ISSN: 0003-4975
Popis: We report metachronous single-lung transplantation for cystic fibrosis after contralateral pneumonectomy. Kyphoscoliosis and mediastinal shift required careful donor-lung sizing with computed tomography and was not dependent on typical parameters. Severe reperfusion injury was treated with nitric oxide, C1-esterase inhibitor, and continuous venovenous hemodialysis. The patient was extubated on the fifth postoperative day and is alive and well. We conclude that single-lung transplantation after contralateral pneumonectomy for patients with cystic fibrosis and an asymmetric chest and evident lung volume mismatch may be an acceptable functional therapeutic option.
Databáze: OpenAIRE