Dengue outbreak 2019: clinical and laboratory profiles of dengue virus infection in Dhaka city
| Autor: | Rudbar Mahmood, Dipak Kumar Mitra, Shakil Ahmed, Tanveer Ahmed, Ahmed Hossain, Md. Shadly Benzadid, Sophie Weston |
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| Přispěvatelé: | Hossain, Ahmed [0000-0003-4575-1273], Apollo - University of Cambridge Repository |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty Abdominal pain Science (General) Pleural effusion Disease Dengue virus medicine.disease_cause Dengue fever Dengue 03 medical and health sciences Q1-390 0302 clinical medicine medicine H1-99 Bangladesh Multidisciplinary Acute dengue infection business.industry Outbreak medicine.disease Rash Social sciences (General) Diarrhea 030104 developmental biology Laboratory parameters Viral infection medicine.symptom business 030217 neurology & neurosurgery Research Article |
| Zdroj: | Heliyon Heliyon, Vol 7, Iss 6, Pp e07183-(2021) |
| ISSN: | 2405-8440 |
| Popis: | Background Dengue fever has been one of the most common mosquito-transmitted diseases in the world, affecting more than 128 countries in both tropical and subtropical regions. Bangladesh has been sufferring from dengue outbreaks almost annually since 2000, and in 2019, Bangladesh faced the worst outbreak of dengue to date. This study aimed to provide clinical and biochemical profiles of Bangladesh's dengue-infected patients. Methods This cross-sectional study was conducted from August through December 2019 in three tertiary private hospitals in Dhaka, Bangladesh. We collected information on demographic data, clinical characteristics, and laboratory profiles for 542 confirmed hospitalized acute dengue cases using a structured questionnaire. Results The average age of the enrolled patients was 26.15 years, and about 50% of patients belonged to the age group of 20–40 years. The most frequent among the prevalent clinical symptoms were fever (93.1%), abdominal pain (29.5%), skin rash (25.3%), and diarrhea (19.7%). 316 patients had some complications, such as breathing problems (41.4%), pleural effusion (38.9%), gum bleeding (11.1%), etc. More than 90% of the patients showed seropositivity for the DENV-NS1 antigen. Conclusions Over the last couple of years, dengue fever has become a major health issue for Bangladesh. To reduce the burden of this disease, timely diagnosis and prompt treatment are necessary. This analysis thus yields the clinical features, laboratory profiles, and seropositivity test results of dengue patients from Bangladesh. The research results may help clinicians understand the circumstantial diagnosis of dengue patients and facilitate early intervention. Dengue; Bangladesh; Laboratory parameters; Acute dengue infection; Viral infection. |
| Databáze: | OpenAIRE |
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