Traumatic brain injury: neuroprotective anaesthetic techniques, an update
| Autor: | Nasser Tawfeeq, Wa'el A Aal-Shaya, Wa’el Taha, Mohammed M Halawani, Khulood Al-Faridi |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
medicine.medical_specialty Xenon Adolescent Traumatic brain injury Resuscitation Intracranial Hypotension Nitrous Oxide Hypoxia ischemia Neuroprotection Perioperative Care Young Adult Hypothermia Induced medicine Craniocerebral Trauma Humans Intensive care medicine Erythropoietin Propofol General Environmental Science Saline Solution Hypertonic Cell Death Isoflurane business.industry Central Nervous System Depressants Middle Aged medicine.disease Hypertonic saline Neuroprotective Agents Anesthesia Brain Injuries Hypoxia-Ischemia Brain Cyclosporine General Earth and Planetary Sciences business Dexmedetomidine |
| Zdroj: | Injury. 40 |
| ISSN: | 1879-0267 |
| Popis: | Traumatic brain injuries remain an area of great challenge to both neurosurgeons and neuroanaesthesiologists. The management of these injuries starts at the scene of the accident. However, strategies for preventing secondary brain injury and its sequelae are continuing to evolve. These strategies include the use of pharmacological and nonpharmacological techniques. Preventing hypoxia and the use of hypertonic saline have been shown to have favourable results on the outcome of these injuries. The use of isoflurane has been shown to have a neuronprotective effect. Propofol is thought to be the future drug of choice because of its neuroprotective properties, although these still need to be further proven through research. In this review an understanding of the pathophysiology of traumatic brain injury will be outlined in order to understand the effects of pharmacological and nonpharmacological agents on secondary brain injury. |
| Databáze: | OpenAIRE |
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