| Autor: |
Samuel Singer, Chris Sander, Fumi Shima, Aimee M. Crago, Nicholas D. Socci, Evan Molinelli, Phaedra Agius, Martin L. Miller, Amanda Craig, Miguel A. López-Lago, Rachael O'Connor, Yawei Shen, Takahiro Mimae, Narasimhan Agaram, Li-Xuan Qin, Ann Y. Lee, Tomoyo Okada |
| Rok vydání: |
2023 |
| DOI: |
10.1158/2159-8290.22531244 |
| Popis: |
Supplementary Figure S1, showing clustering of myxofibrosarcomas compared to normal tissue and showing the validation of the association of 5 genes with survival. Supplementary Figure S2, showing the effects of ITGA10 knockdown and overexpression. Supplementary Figure S3, showing the cell biology of integrin-alpha10 in myxofibrosarcoma cells. Supplementary Figure S4, showing the associations of TRIO and RICTOR amplification and overexpression with clinical outcomes. Supplementary Figure S5, showing that TRIO and RAC1 knockdown induce apoptosis in myxofibrosarcoma cells, but not in ASCs. Supplementary Figure S6, showing that RAPTOR knockdown does not induce apoptosis in myxofibrosarcoma cells. Supplementary Figure S7, showing the effects of RAC/PAK and mTOR inhibitors in myxofibrosarcoma cells and normal cells. Supplementary Figure S8, showing that mice treated with INK128 and/or EHop-016 maintain their weight. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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