Characteristics of computed tomography perfusion parameters in non-small-cell-lung-cancer and its relationship to histology, size, stage an treatment response
| Autor: | Roque Oca Pernas, Maria González Vázquez, Antonio Vaamonde Liste, Miguel Souto Bayarri, Carlos Delgado Sánchez-Gracián, Carmen Trinidad López, Javier de la Fuente Aguado, Gonzalo Tardáguila de la Fuente |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Lung Neoplasms Imaging biomarker Perfusion Imaging medicine.medical_treatment Perfusion scanning 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Carcinoma Non-Small-Cell Lung Humans Medicine Radiology Nuclear Medicine and imaging Prospective Studies Stage (cooking) Lung cancer Prospective cohort study Aged Aged 80 and over business.industry Middle Aged medicine.disease Radiation therapy Treatment Outcome 030220 oncology & carcinogenesis T-stage Female Tomography X-Ray Computed business Nuclear medicine Perfusion |
| Zdroj: | Clinical Imaging. 50:5-12 |
| ISSN: | 0899-7071 |
| Popis: | Objectives To analyze computed tomography perfusion (CTP) parameters in NSCLC. Materials and methods Prospective study, 152 patients with NSCLC. CTP parameters were correlated with histology, stage, size and response to conventional chemotherapy/radiotherapy. Results Neuroendocrine tumours presented higher BV (p 0.002). Negative correlation of PMB (p 0.003) and positive of MTT (p 0.046) with T stage was found. BF showed negative correlation with size. No differences were found with the RECIST levels of response to chemotherapy/radiotherapy. Conclusions CTP parameters were highly variable. Neuroendocrine tumours presented higher BV and PMB values. Perfusion parameters do not differ depending on the stage and do not predict response to treatment. |
| Databáze: | OpenAIRE |
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