Design of a Hypersensitive pH-Sensory System Created by a Combination of Charge Neutralization and Aggregation-Induced Emission (AIE)
| Autor: | Tatsuhiro Yamamoto, Bappaditya Roy, Junji Sakamoto, Seiji Shinkai, Daisuke Yoshihara, Takao Noguchi |
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| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
Organic Chemistry Analytical chemistry Sensory system General Chemistry 010402 general chemistry 01 natural sciences Catalysis Neutralization 0104 chemical sciences chemistry.chemical_compound chemistry Ph range Biophysics sense organs Self-assembly Neutral ph Aggregation-induced emission Boronic acid |
| Zdroj: | Chemistry - A European Journal. 23:17663-17666 |
| ISSN: | 0947-6539 |
| Popis: | In our bodies, a slight pH change causes remarkable activation or serious damage in the biological processes and continuously keeps biological homeostasis. Detection of such a slight pH change has been a constant demand in searching for unusual biological events. In this paper, we demonstrate a novel pH sensory system that has been achieved through a combination of charge neutralization by a slight pH change with aggregation-induced emission (AIE). We selected a cyano-functionalized oligo(phenylene-vinylene) (cyanoOPV) backbone for AIE and introduced ammonium-tethered boronic acid groups as a pH-dependent function. The self-assembling of these dyes (OPV-Cn) was readily achieved by pH-dependent charge neutralization at the neutral pH region. This sensory system showed unusually sensitive pH responsiveness in a narrow pH range. Moreover, this pH change was observed in a biologically important neutral pH region. We therefore believe that this system is broadly applicable to detect the slight pH change occurring in the biological events. |
| Databáze: | OpenAIRE |
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