The Differential Diagnostic Values of Cytokine Levels in Pleural Effusions

Autor: Erdal Yilmaz, A. Denizmen Aygün, A. Nese Citak Kurt, Ahmet Gödekmerdan, Saadet Akarsu, Yasar Dogan
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Zdroj: Mediators of Inflammation, Vol 2005, Iss 1, Pp 2-8 (2005)
Mediators of Inflammation
ISSN: 1466-1861
0962-9351
Popis: The aim is to examine whether the changes in pleural fluid interleukin (IL)-1β, IL-2, IL-6, and IL-8 levels were significant in differential diagnosis of childhood pleural effusions. IL-1β, IL-2, IL-6, and IL-8 levels in pleural fluids of all 36 patients were measured. The levels of IL-1β, IL-2, IL-6, and IL-8 in pleural fluids were statistically significantly higher in the transudate group compared with those of the exudate group. The levels of IL-1β, IL-6, and IL-8 were also found to be statistically significantly higher in the empyema group compared with both the parapneumonic and the tuberculous pleural effusion groups. The levels of IL-2 and IL-6 were detected to be statistically significantly higher in the tuberculous pleural effusion group in comparison with those of the parapneumonic effusion group. The results showed that pleural fluids IL-1β, IL-2, IL-6, and IL-8 could be used in pleural fluids exudate and transudate distinction.
Databáze: OpenAIRE