Physiologic and Metabolic Magnetic Resonance Imaging in Gliomas
| Autor: | Larry Junck, Thomas T. Chenevert, Yue Cao, Pia C. Sundgren, Christina Tsien |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty Magnetic Resonance Spectroscopy medicine.diagnostic_test business.industry Brain tumor Soft tissue Magnetic resonance imaging Vascular permeability Glioma medicine.disease Magnetic Resonance Imaging Central Nervous System Neoplasms Diffusion Magnetic Resonance Imaging Oncology In vivo medicine Humans business Radiation treatment planning Perfusion |
| Zdroj: | Journal of Clinical Oncology. 24:1228-1235 |
| ISSN: | 1527-7755 0732-183X |
| Popis: | Magnetic resonance (MR) imaging provides excellent soft tissue differentiation and in vivo assessment of physiologic and metabolic properties of tissue. As new and more aggressive treatment modalities and combined modalities are being investigated for brain tumor treatment, it is becoming more important to accurately define tumor volumes for treatment planning, to determine the most aggressive tumor regions for intensified radiation treatment, to identify early regional response to therapy for reoptimization of treatment, and to detect early indicators of developing normal tissue toxicity. Readily available MR techniques of physiologic and metabolic imaging can currently provide useful information regarding tumor tissue properties including chemical composition, cerebral blood volume, perfusion, vascular permeability, and water mobility. This article will focus on the potential value of MR physiologic and metabolic imaging in the clinical management of malignant gliomas. |
| Databáze: | OpenAIRE |
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