West Nile virus encephalitis: A report of two cases and review of neuroradiological features
| Autor: | Shitiz Sriwastava, Medha Tandon, Dhairya A. Lakhani, John C Mach, Christopher Bailey, Saurabh Kataria |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
Pathology medicine.medical_specialty viruses lcsh:R895-920 Case Report Disease Arbovirus 030218 nuclear medicine & medical imaging White matter 03 medical and health sciences PCR polymerase chain reaction 0302 clinical medicine Cerebrospinal fluid Meningoencephalitis Basal ganglia medicine Radiology Nuclear Medicine and imaging biology medicine.diagnostic_test business.industry virus diseases Magnetic resonance imaging biology.organism_classification medicine.disease IVIG intravenous immunoglobulin Flavivirus WNV West Nile virus medicine.anatomical_structure WNND West Nile neuroinvasive disease business MRI magnetic resonance imaging West Nile virus 030217 neurology & neurosurgery |
| Zdroj: | Radiology Case Reports, Vol 15, Iss 11, Pp 2422-2426 (2020) Radiology Case Reports |
| ISSN: | 1930-0433 |
| Popis: | West Nile virus (WNV) is a single-stranded RNA arbovirus of Flavivirus genus that is endemic to the United States and known to cause neuroinvasive disease. Diagnosis is confirmed by the presence of WNV-specific IgM antibodies within serum or cerebrospinal fluid (CSF). Radiologically, it presents as hyperintense T2 signal within deep brain structures (ie, thalami and mid-brain) with or without cerebral peduncle and substantia nigra involvement. On diffusion-weighted imaging, restricted diffusion is reported in basal ganglia and disseminated throughout the white matter. In this report, we describe the imaging findings for 2 cases of WNV from our institution; a 56-year-old female and a 34-year-old female. Increased vigilance for WNV is warranted, particularly in immunosuppressed patients presenting with a clinical picture of viral meningoencephalitis despite initial negative magnetic resonance imaging or CSF analysis. A high suspicion for WNV disease should prompt repeat imaging or laboratory workup. |
| Databáze: | OpenAIRE |
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