Measuring the Ocular Morphological Parameters of Guinea Pig Eye with Edge Detection and Curve Fitting
Autor: | Zhong-Bao Qiao, Hai-Yun Ye, Wen-Ting Luo, Xingtao Zhou, Tong Qiao, Ying Huang, Na Lu, Ya-Jing Yang, Yue Di |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Models
Anatomic genetic structures Article Subject Computer applications to medicine. Medical informatics Guinea Pigs R858-859.7 Diagnostic Techniques Ophthalmological Eye General Biochemistry Genetics and Molecular Biology Edge detection Radius of curvature (optics) law.invention Cornea 03 medical and health sciences 0302 clinical medicine law medicine Image Processing Computer-Assisted Photography Animals Humans Computer Simulation 030304 developmental biology Physics 0303 health sciences General Immunology and Microbiology Keratometer Applied Mathematics Computational Biology General Medicine Mathematical Concepts Circumference eye diseases medicine.anatomical_structure Tilt (optics) Modeling and Simulation Models Animal 030221 ophthalmology & optometry Curve fitting sense organs Eccentricity (mathematics) Biomedical engineering Research Article |
Zdroj: | Computational and Mathematical Methods in Medicine Computational and Mathematical Methods in Medicine, Vol 2020 (2020) |
ISSN: | 1748-670X |
DOI: | 10.1155/2020/6689023 |
Popis: | Aim. To identify the guinea pig eyeball with edge detection and curve fitting and devise a noncontact technology of measuring ocular morphological parameters of small experimental animal. Methods. Thirty-nine eyeballs of guinea pig eyeballs were photographed to obtain the anterior and posterior surface; transverse and sagittal planes after the eyeballs were eviscerated. Next, the eyeball photos were input into digital image analysis software; the corresponding photo pixels-actual length ratio was acquired by a proportional scale. The contour lines of the eyeballs were identified by edge detection technology; conic curve fitting was applied to fit the contour line of the eyeball. The maximum and minimum diameters, the horizontal and vertical diameters, eccentricity, tilt angle, cross-sectional area, equatorial circumference, retrobulbar equatorial maximum length, corneal radius of curvature (CRC) in central region, and the whole cornea were calculated according to the geometric principles. The corneal data of in vitro study were compared with the in vivo results. Results. The contour line of the selected guinea pig eye was identified correctly by edge detection. There were no significant differences between anterior and posterior surfaces of one eyeball in the maximum diameters, eccentricity, cross-sectional area, equatorial circumference, and tilt angle ( P > 0.01 ). There were significant differences of eccentricity and CRC between central region and the whole cornea ( P < 0.01 ). There were no significant differences between keratometer in vivo and cornea in vitro. Conclusion. It was feasible to measure an experimental animal eye in a noncontact way. Edge detection and curve fitting technology could accurately evaluate the ocular morphological parameters. |
Databáze: | OpenAIRE |
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