Coronary artery ectasia: prevalence, angiographic characteristics and clinical outcome

Autor: Anees Musallam, Scott Ehrenberg, Nadav Asher Willner, Ariel Roguin
Rok vydání: 2019
Předmět:
0301 basic medicine
Adult
Male
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty
Time Factors
Heart disease
030204 cardiovascular system & hematology
Conservative Treatment
Coronary Angiography
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Ectasia
medicine.artery
Internal medicine
Prevalence
Medicine
Humans
Myocardial infarction
Israel
Aged
Retrospective Studies
Aged
80 and over
medicine.diagnostic_test
coronary stenting
business.industry
Coronary artery ectasia
Coronary Aneurysm
Middle Aged
medicine.disease
Coronary Vessels
Interventional Cardiology
030104 developmental biology
medicine.anatomical_structure
Treatment Outcome
lcsh:RC666-701
Right coronary artery
Angiography
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
coronary artery disease
Artery
Dilatation
Pathologic
Zdroj: Open Heart
Open Heart, Vol 7, Iss 1 (2020)
ISSN: 2053-3624
Popis: ObjectiveDetermine coronary artery ectasia (CAE) prevalence and clinical outcome in a large cohort of patients underwent coronary angiography.MethodsIn an 11-year period, between 2006 and 2017, 20 455 coronary angiography studies were performed at a large university centre. Patients diagnosed with CAE based on procedure report were included in the final analysis.ResultsCAE was diagnosed in 174 out of 20 455 studies (0.85% per total angiograms, 161 patients). Patients’ average age was 59.6±11.2 years old with male predominance (90.7%). Diffuse ectasia morphology was most common (78.9%), followed by fusiform (16.1%) and saccular (5%). Mixed CAE and atherosclerotic heart disease (ASHD) was present in 75.2% of the patients and isolated CAE in 24.8%. The most common coronary artery involved was the right coronary artery (RCA) (79%). Following index angiography, all the isolated CAE group was managed conservatively, while 67% of the mixed CAE-ASHD group underwent coronary intervention. In an average follow-up of 6±3.6 years, adverse clinical event (a composite endpoint of any death, cerebrovascular accident, myocardial infarction, thromboembolic event, bleeding and stent thrombosis) occurred in 48.8% of the mixed CAE-ASHD group compared with 25% in the isolated CAE group (pConclusionsCAE is a rare phenomenon. The most common artery involved was the RCA, and the diffused type of CAE was the most frequent. Most patients with CAE have also concomitant ASHD, and those patients have higher mortality and complications rate, compared with isolated CAE disease.
Databáze: OpenAIRE
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