Autologous immune enhancement therapy against an advanced epithelioid sarcoma: A case report
| Autor: | Baskar Subramani, Kohila Krishnan, Abhi Veerakumarasivam, Manjunath Sadananda Rao, Kananathan Ratnavelu, Sheela Devi Sugadan, Xuewen Deng, Chithra Ramanathan Pullai, Terunuma Hiroshi |
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| Rok vydání: | 2013 |
| Předmět: |
autologous immune enhancement therapy
Autologous immune enhancement therapy Oncology Cancer Research medicine.medical_specialty Chemotherapy Pathology natural killer cells Oncogene business.industry Epithelioid sarcoma medicine.medical_treatment T cells Cancer Articles Immunotherapy medicine.disease Molecular medicine advanced epithelioid sarcoma Internal medicine medicine adverse reactions Adverse effect business |
| Zdroj: | Oncology Letters |
| ISSN: | 1792-1082 1792-1074 |
| DOI: | 10.3892/ol.2013.1247 |
| Popis: | Rare types of cancer are often not effectively treated by approaches such as chemotherapy and radio- therapy, although their side-effects persist. Immunotherapy has been gaining attention worldwide with growing examples of its anticancer activity demonstrated in vivo. This case report describes a 35-year-old male who suffered from advanced epithelioid sarcoma and underwent 18 cycles of chemotherapy without any significant response, who suffered adverse effects that caused lung collapse. A notable response was observed following the administration of autologous immune enhancement therapy (AIET), which involves a process of isolation, activation and expansion of natural killer (NK) and T cells, which were obtained from the patient's own (autologous) peripheral blood. With the present data and the response of the patient to AIET, it may be proposed that AIET is beneficial for patients suffering from advanced epithelioid sarcoma without producing adverse effects. |
| Databáze: | OpenAIRE |
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