Juvenile nasopharyngeal angiofibromas in Denmark 1981-2003: diagnosis, incidence, and treatment
| Autor: | B L Petersen, Ben Vainer, H Glad, Sune A. Theilgaard, Christian von Buchwald, John Jakobsen, P Bonvin, C Lajer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Juvenile nasopharyngeal angiofibroma Denmark medicine.medical_treatment Blood Loss Surgical Nasopharyngeal neoplasm Angiofibroma Cohort Studies medicine Humans Juvenile Embolization Child Neoadjuvant therapy Neoplasm Staging Retrospective Studies business.industry Incidence Incidence (epidemiology) Endoscopy Nasopharyngeal Neoplasms General Medicine medicine.disease Combined Modality Therapy Embolization Therapeutic Angiofibromas Neoadjuvant Therapy Surgery Cross-Sectional Studies Otorhinolaryngology business |
| Zdroj: | Glad, H, Vainer, B, Buchwald, C, Petersen, B L, Theilgaard, S A, Bonvin, P, Lajer, C & Jakobsen, J 2007, ' Juvenile nasopharyngeal angiofibromas in Denmark 1981-2003: diagnosis, incidence, and treatment ' Acta Oto-Laryngologica, vol. 127, no. 3, pp. 292-299 . Glad, H, Vainer, B, Buchwald, C, Petersen, B L, Theilgaard, S A, Bonvin, P, Lajer, C & Jakobsen, J 2007, ' Juvenile nasopharyngeal angiofibromas in Denmark 1981-2003 : diagnosis, incidence, and treatment ', Acta Oto-Laryngologica, vol. 127, no. 3, pp. 292-9 . https://doi.org/10.1080/00016480600818138 |
| DOI: | 10.1080/00016480600818138 |
| Popis: | CONCLUSIONS: Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor in young males, with a non-negligible potential for recurrence. Preoperative embolization is a safe procedure that diminishes the peroperative blood loss and the need for blood transfusion. The endoscopic approach was used with good results in JNA stage I and II (Chandler). OBJECTIVES: To estimate the incidence rate of JNA in the Danish population and to describe symptoms and treatment. PATIENTS AND METHODS: This was a national retrospective cohort study. All cases of JNA diagnosed in Denmark from 1981 to 2003 were identified. Data were extracted from medical records. RESULTS: Forty-five male (no female) JNA cases were identified. In 43 cases, clinical data were recovered. Median age was 15 years. The incidence rate in Denmark was 0.4 cases per million inhabitants per year and 3.7 cases per million males (aged 10-24) per year. All patients underwent surgery, and the endoscopic approach was increasingly being used. The embolization procedure proved to be safe and decreased the intraoperative blood loss statistically to 650 ml in the embolized group from an average of 1200 ml in the non-embolized group (p Udgivelsesdato: 2007-Mar |
| Databáze: | OpenAIRE |
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