How safe is the use of prosthetic materials in the repair of abdominal-wall defects in malnourished subjects?
| Autor: | Demet Yilmazer, Kemal Serbetci, Aysel Kiziltay, Alper Yavuz, Mehmet Ali Karahan, Nesrin Hasirci, Ozge Captug, Hakan Kulacoglu, Hasan Bilgili, Duray Şeker, Zafer Ergul |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
business.industry Maternal and child health medicine.medical_treatment Significant difference wound healing General Medicine malnutrition Histopathological examination Hernia repair Infection rate Surgery Abdominal wall Polypropylene mesh medicine.anatomical_structure mesh tensile strength medicine Medicine business Wound healing hernia repair |
| Zdroj: | Open Medicine, Vol 4, Iss 3, Pp 331-336 (2009) |
| ISSN: | 2391-5463 |
| Popis: | Incisional hernias and abdominal-wall defects consume large amounts of healthcare resources. Use of mesh is effective in treatment of these disorders and can decrease the rate of recurrence. This experimental study focused on the safety of mesh use in the setting of malnutrition, a condition that impairs wound healing. Rats were divided into two groups: normally fed and food-restricted. An abdominal-wall defect, 2 by 2 cm, was covered with polypropylene mesh, 2.5 by 2.5 cm. After sacrifice of the rats at the 21st and 60th days, tissue samples were sent for tensiometric and histopathological studies. No significant difference in infectious complications was observed between the two groups. Tensiometry revealed no significant differences between the groups. On histopathological examination, the only difference noted was in the vascularization scores of normally fed rats. For malnourished subjects that survived after surgery, the use of polypropylene mesh appeared safe in the closure of abdominal-wall defects, with no increase in infection rate and satisfactory wound healing. |
| Databáze: | OpenAIRE |
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