Clinical Characteristics and Outcome of Bloodstream Infections in HIV-Infected Patients with Cancer and Febrile Neutropenia: A Case–Control Study

Autor: Juan Ambrosioni, Josep Mensa, Montserrat Rovira, Josep Mallolas, José Antonio Martínez, Francesc Marco, Celia Cardozo, Jordi Esteve, Estela Moreno-García, Marta Hernández-Meneses, Alex Soriano, Mariana Chumbita, Felipe García, Carolina Garcia-Vidal, Nicole Garcia-Pouton, Pedro Puerta-Alcalde, José M. Miró
Rok vydání: 2021
Předmět:
Zdroj: Infectious Diseases and Therapy. 10:955-970
ISSN: 2193-6382
2193-8229
DOI: 10.1007/s40121-021-00445-3
Popis: We aimed to compare the clinical characteristics and outcomes of bloodstream infections (BSI) in cancer patients presenting febrile neutropenia with and without HIV infection, and analyze the prognostic factors for mortality. BSI episodes in febrile neutropenic patients following chemotherapy were prospectively collected (1997–2018). A case (HIV-infected)–control (non-HIV-infected) sub-analysis was performed (1:2 ratio), matching patients by age, gender, baseline disease, and etiological microorganism. From 1755 BSI episodes in neutropenic cancer patients, 60 (3.4%) occurred in those with HIV. HIV characteristics: 51.7% were men who have sex with men; 58.3% had
Databáze: OpenAIRE