263: Atherosclerotic complications of hemodialysis in Marrakech

Autor: Dounia Benzarouel, Khadija Hasni, Mustafa El Hattaoui
Rok vydání: 2013
Předmět:
Zdroj: Archives of Cardiovascular Diseases Supplements. 5(1)
ISSN: 1878-6480
DOI: 10.1016/s1878-6480(13)71194-7
Popis: Introduction Atherosclerotic disease are a severe complications in uremic patients. They result in particular by an increased frequency of coronary ischemic events, responsible for 8-15% of deaths. The purpose of this study is to evaluate the frequency and severity of atherosclerotic complications in this population and their associations with traditional risk factors and specific uremia. Patients and methods This is a multicenter cross-sectional study, only prospective 6-months from March 2011 to August 2011, including 130 hemodialysis. Complications were defined by atherosclerotic coronary artery disease, cerebrovascular disease and peripheral vascular disease. They were classified according to severity using an index of existing co morbidities (ICED). Comparison of patients with and without atherosclerotic complications was performed using SPSS software Results The frequency of atherosclerotic complications was 29.2% (38 patients).21 patients had coronary artery disease (16.2%), 7 patients had cerebrovascular disease (5.4%) and 16 patients had cerebrovascular disease (12.3%). The mean age was 55.6 ± 8.96 years. We noted a male predominance. 6 patients were smokers, 30 patients had hypertension and 17 patients were diabetic. Dyslipidemia was found in 13 patients. Coronary angiography was performed in 13 patients showing single-vessel disease 4 patients, 2 patients vessel disease and vessel disease in 1 patient. 5 patients had an ischemic stroke which was a transient. 1 patient had a hemorrhagic stroke and one patient had a carotid stenosis. 3 patients had peripheral arterial disease confirmed and 11 patients had intermittent claudication of the lower limbs. Atherosclerotic complications were significantly associated with age (p=0.001), hypertension (p=0.048), systolic blood pressure (p=0.038), diabetes (p=0.001), dyslipidemia (p=0.024), obesity (p=0.018), triglycerides (p=0.018) and left ventricular mass (p=0.003). Conclusion Uremic patients have a high incidence of atherosclerotic disease and traditional cardiovascular risk factors.
Databáze: OpenAIRE
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