The influence of contrast agents on hemorrhage produced by lithotripter fields
| Autor: | Robert J. Mayer, Carol H. Raeman, Sally Z. Child, Diane Dalecki, Edwin L. Carstensen, David P. Penney |
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| Rok vydání: | 1997 |
| Předmět: |
Lung Diseases
Pathology medicine.medical_specialty Acoustics and Ultrasonics medicine.medical_treatment Biophysics Positive pressure Contrast Media Hemorrhage Lithotripsy Skin Diseases Mice Seminal vesicle Albumins medicine Animals Ultrasonics Radiology Nuclear Medicine and imaging Hematuria Kidney Acoustic field Lung Radiological and Ultrasound Technology business.industry Stomach Microspheres Disease Models Animal medicine.anatomical_structure Exposure period Gastrointestinal Hemorrhage business |
| Zdroj: | Ultrasound in Medicine & Biology. 23:1435-1439 |
| ISSN: | 0301-5629 |
| Popis: | Ultrasonic contrast agents greatly increase the side effects of low-amplitude lithotripter fields in mice. Using a piezoelectric lithotripter, adult mice were exposed to 200 lithotripter pulses with a peak positive pressure amplitude of 2 MPa. During the exposure period, mice were injected with approximately 0.1 mL of the ultrasonic contrast agent Albunex. For comparison, another group of mice experienced the same lithotripter exposures, but were not injected with contrast agent. Following exposures, animals were sacrificed and observed for hemorrhage in various organs and tissues. Mice exposed to the lithotripter field alone had minimal hemorrhage only in the intestine and lung. In comparison, mice injected with Albunex during exposure exhibited extensive hemorrhage in the intestine, kidney, muscle, mesentery, stomach, bladder, seminal vesicle and fat. |
| Databáze: | OpenAIRE |
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