Cardiac imaging in patients with chronic kidney disease
| Autor: | Philip A. Kalra, Smeeta Sinha, Nik Abidin, Darren Green, Diana Y. Y. Chiu |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Heart Diseases Heart disease business.industry medicine.medical_treatment Population Coronary Stenosis medicine.disease Left ventricular hypertrophy Coronary artery disease Cardiac Imaging Techniques Nephrology Internal medicine Cardiology medicine Humans Renal replacement therapy Renal Insufficiency Chronic business education Algorithms Cardiac imaging Kidney disease |
| Zdroj: | Nature Reviews Nephrology. 11:207-220 |
| ISSN: | 1759-507X 1759-5061 |
| DOI: | 10.1038/nrneph.2014.243 |
| Popis: | Patients with chronic kidney disease have a high risk of developing cardiovascular disease but diagnosis of cardiovascular dysfunction in this population is complicated. In this Review, the authors describe cardiac imaging techniques that can be used to detect gross cardiac structure and function, coronary calcification, wall motion abnormalities and coronary artery disease, and discuss the benefits and difficulties in using these techniques in patients with chronic kidney disease. Patients with chronic kidney disease (CKD) carry a high cardiovascular risk. In this patient group, cardiac structure and function are frequently abnormal and 74% of patients with CKD stage 5 have left ventricular hypertrophy (LVH) at the initiation of renal replacement therapy. Cardiac changes, such as LVH and impaired left ventricular systolic function, have been associated with an unfavourable prognosis. Despite the prevalence of underlying cardiac abnormalities, symptoms may not manifest in many patients. Fortunately, a range of available and emerging cardiac imaging tools may assist with diagnosing and stratifying the risk and severity of heart disease in patients with CKD. Moreover, many of these techniques provide a better understanding of the pathophysiology of cardiac abnormalities in patients with renal disease. Knowledge of the currently available cardiac imaging modalities might help nephrologists to choose the most appropriate investigative tool based on individual patient circumstances. This Review describes established and emerging cardiac imaging modalities in this context, and compares their use in CKD patients with their use in the general population. |
| Databáze: | OpenAIRE |
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