Impact of a Novel Smartphone App (CureApp Smoking Cessation) on Nicotine Dependence: Prospective Single-Arm Interventional Pilot Study

Autor: Kazuma Sekine, Tomoko Betsuyaku, Eriko Morino, Kohta Satake, Riri Watanabe, Koichi Fukunaga, Hiroki Tateno, Katsunori Masaki, Naofumi Kameyama, Tomohiro Ono, Shin Suzuki, Akihiro Nomura
Rok vydání: 2019
Předmět:
Adult
Male
medicine.medical_specialty
Telemedicine
020205 medical informatics
medicine.medical_treatment
media_common.quotation_subject
Pilot Projects
Health Informatics
Craving
Information technology
02 engineering and technology
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Japan
Internal medicine
0202 electrical engineering
electronic engineering
information engineering
medicine
Clinical endpoint
Humans
Outpatient clinic
Prospective Studies
030212 general & internal medicine
nicotine dependence
smartphone application
Varenicline
digital therapeutics
media_common
Original Paper
business.industry
Therapeutic effect
Tobacco Use Disorder
Middle Aged
Abstinence
T58.5-58.64
Mobile Applications
smoking cessation
chemistry
Smoking cessation
Female
telemedicine
Public aspects of medicine
RA1-1270
medicine.symptom
business
Zdroj: JMIR mHealth and uHealth, Vol 7, Iss 2, p e12694 (2019)
JMIR mHealth and uHealth
ISSN: 2291-5222
DOI: 10.2196/12694
Popis: BackgroundMobile apps have been considered to provide active and continuous support for smoking cessation. However, it is yet to be known whether a smoking cessation smartphone app improves long-term abstinence rates in nicotine-dependent patients. ObjectiveThis study aimed to evaluate the long-term abstinence effect of a novel smartphone app, CureApp Smoking Cessation (CASC), in patients with nicotine dependence. MethodsIn this prospective, interventional, multicenter, single-arm study, we provided the CASC app to all the participants, who used it daily for 24 weeks. The CASC app includes features to maximize the therapeutic effect of pharmacological therapies and counseling at outpatient clinics for smoking cessation. The primary endpoint was a continuous abstinence rate (CAR) from weeks 9 to 24, whereas secondary endpoints were CARs from weeks 9 to 12 and 9 to 52. ResultsOf the 56 adult smokers recruited, 1 did not download the app; therefore, 55 participants constituted the full analysis sample. The CAR from weeks 9 to 24 was 64% (35/55, 95% CI 51%-76%), whereas the CARs from weeks 9 to 12 and 9 to 52 were 76% (42/55, 95% CI 65%-88%) and 58% (32/55, 95% CI 46%-71%), respectively. These CARs were better than the results of the national survey on outpatient clinics with regard to smoking cessation under the National Health Insurance Program and that of the varenicline phase 3 trial in Japan and the United States. There was only 1 participant who dropped out during the 12 weeks of the treatment period. This treatment decreased the scores related to withdrawal and craving symptoms. ConclusionsThe addition of CASC to usual smoking cessation therapies resulted in high CARs, high patient retention rates, and improvement of cessation-related symptoms. The smartphone app CASC is a feasible and useful tool to help long-term continuous abstinence that can be combined with a standard smoking cessation treatment program.
Databáze: OpenAIRE
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