Osteonecrosis maxilar secundaria al uso de bisfosfonatos por vía oral: Exposición de tres casos clínicos relacionados con alendronato

Autor:	Manuel Sosa-Henríquez, Sacramento Bocanegra-Pérez, Milan Knezevic, José María Castellano-Navarro, Arwen Gebaguer Blanco, Mario Vicente-Barrero
Jazyk:	Spanish; Castilian
Rok vydání:	2009
Předmět:	medicine.medical_specialty Biphosphonates business.industry Diphosphonates Alendronates Osteonecrosis General Medicine medicine.disease Purulent discharge Surgery Biphosphonate medicine medicine.symptom Bone pain Complication Osteonecrosis of the jaw business
Zdroj:	Revista médica de Chile v.137 n.2 2009 SciELO Chile CONICYT Chile instacron:CONICYT
Popis:	Osteonecrosis of the jaw associated to biphosphonate use is more common in cancer patients with bone metastases, that are using intravenous diphosphonates. When these drugs are used orally the risk of the complication is lower. We report 3 diabetic women aged 69, 76 and 82 years, receiving alendronate 70 mg every one week. The unveiling event was the extraction of several teeth without the use of antibiotics. All had bone pain, purulent discharge, loss of bone and halitosis. All improved five months after discontinuing alendronate.
Databáze:	OpenAIRE
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