Additional file 2: Figure S1. of The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations

Autor: Kines, Kristine, Sokolowski, Mark, DeHaro, Dawn, Claiborne Christian, Baddoo, Melody, Smither, Madison, Belancio, Victoria
Rok vydání: 2016
DOI: 10.6084/m9.figshare.c.3629300_d9
Popis: Alignment of mutations in the ORF2 endonuclease domain from full-length human L1 loci. Bioinformatic analysis using L1Base [35] revealed numerous mutations in the ORF2 endonuclease domains of 134 intact, full-length L1 loci. The ORF2 endonuclease domain sequences (amino acids 1â 239) from these 134Â L1 loci were aligned using the Clustal W method. The chromosome and L1Base ID number for each loci is listed in the column on the left. Mutations relative to the L1.3 ORF2 endonuclease domain sequence are indicated by the blue square above the amino acid residues. Dots indicate a match to the L1.3 sequence and mutations are denoted by the single letter amino acid code. (PDF 45Â kb)
Databáze: OpenAIRE