Virus-associated haemophagocytic syndrome with Epstein-Barr virus infection
| Autor: | Kohichi Ohshima, Fuyuki Eguchi, Shinichi Kobari, Hideko Tasaka, Masahiro Kikuchi |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Herpesvirus 4
Human Pathology medicine.medical_specialty Histiocytosis Non-Langerhans-Cell Molecular Sequence Data Genome Viral Biology medicine.disease_cause Virus Herpesviridae Pathology and Forensic Medicine Necrosis Bone Marrow hemic and lymphatic diseases medicine Humans Child Antigens Viral Molecular Biology Lymph node Epstein–Barr virus infection Histiocyte Base Sequence Nucleic Acid Hybridization Histiocytes Cell Biology General Medicine medicine.disease Epstein–Barr virus Virology Tumor Virus Infections medicine.anatomical_structure Ferritins Female Lymph Nodes Lymph Bone marrow |
| Zdroj: | Virchows Archiv A Pathological Anatomy and Histopathology. 419:519-522 |
| ISSN: | 1432-2307 0174-7398 |
| Popis: | The clinical and histological findings of a 10-year-old girl with virus-associated haemophagocytic syndrome are presented. The serum levels of Epstein-Barr viral antigens were elevated. Epstein-Barr virus (EBV) genome was detected by polymerase chain reaction in bone marrow and lymph node specimens. Histologically, haemophagocytic histiocytes were present in bone marrow, and areas of non-suppurative necrosis were present in lymph nodes, where silver grain deposition of the EBV genome was demonstrated by in situ hybridization. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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