Correlation between computer-aided dynamic gadolinium-enhanced MRI assessment of inflammation and semi-quantitative synovitis and bone marrow oedema scores of the wrist in patients with rheumatoid arthritis--a cohort study
| Autor: | Henning Bliddal, Kim Hørslev-Petersen, Rasmus Bouert, Mikael Boesen, Bente Danneskiold-Samsøe, Mette B. Axelsen, Mikkel Østergaard, Marco A. Cimmino, Olga Kubassova |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Wrist Joint medicine.medical_specialty Arthritis Contrast Media Gadolinium Wrist computer.software_genre Arthritis Rheumatoid Young Adult Rheumatology Voxel Region of interest Synovitis Image Interpretation Computer-Assisted medicine Edema Humans Pharmacology (medical) Bone Marrow Diseases Rank correlation Aged medicine.diagnostic_test business.industry Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Rheumatoid arthritis Radiology business Epidemiologic Methods computer |
| Zdroj: | Boesen, M, Kubassova, O, Bouert, R, Axelsen, M B, Ostergaard, M, Cimmino, M A, Danneskiold-Samsøe, B, Hørslev-Petersen, K & Bliddal, H 2012, ' Correlation between computer-aided dynamic gadolinium-enhanced MRI assessment of inflammation and semi-quantitative synovitis and bone marrow oedema scores of the wrist in patients with rheumatoid arthritis--a cohort study ', Rheumatology, vol. 51, no. 1, pp. 134-43 . https://doi.org/10.1093/rheumatology/ker220 |
| ISSN: | 1462-0332 |
| DOI: | 10.1093/rheumatology/ker220 |
| Popis: | OBJECTIVE To test the correlation between assessment of inflammation using dynamic contrast-enhanced MRI (DCE-MRI) analysed by a novel computer-aided approach and semi-quantitative scores of synovitis and bone marrow oedema (BME) using the OMERACT-RA MRI Scoring (RAMRIS) system, in the wrist of patients with RA. METHODS Fifty-four RA patients had conventional and DCE-MRI of a symptomatic wrist using a low-field 0.2T extremity scanner. RAMRIS synovitis and BME of the wrist joint were done. DCE-MRI data were analysed in three ways: (i) in all images (fully automated approach), (ii) within a large extended region of interest (ROI) placed around the wrist joint (semi-automated approach) and (iii) within a small ROI placed in the area with most visual enhancement (semi-automated approach). Time spent on each procedure was noted. Spearman's rank correlation test was applied to assess the correlation between RAMRIS and the computer-generated dynamic parameters. RESULTS RAMRIS synovitis (range 2-9), BME (range 0-39) and the dynamic parameters reflecting the number of enhancing voxels were significantly correlated, especially when an extended ROI around the wrist was used (ρ = 0.74; P |
| Databáze: | OpenAIRE |
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