Ocular abnormalities in morbid obesity
| Autor: | Sami Dogan, Murat Kaya, Kuddusi Teberik, M. Tahir Eski, Mevlüt Pehlivan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Intraocular pressure Eye disease Nerve fiber layer Glaucoma Body Mass Index Morbid obesity chemistry.chemical_compound 0302 clinical medicine lcsh:Ophthalmology Corneal pachymetry medicine.diagnostic_test General Medicine Middle Aged Anterior eye segment Obesity Morbid medicine.anatomical_structure Female Tomography Optical Coherence Retinopathy Adult medicine.medical_specialty Adolescent Nerve fibers Retina Statistics Nonparametric 03 medical and health sciences Tonometry Ocular Young Adult Retinal Diseases Ophthalmology medicine Posterior eye segment Humans business.industry Choroid Retinal Choroid Diseases medicine.disease eye diseases chemistry lcsh:RE1-994 Case-Control Studies 030221 ophthalmology & optometry sense organs business Body mass index |
| Zdroj: | Arquivos Brasileiros de Oftalmologia, Vol 82, Iss 1, Pp 6-11 Arquivos Brasileiros de Oftalmologia v.82 n.1 2019 Arquivos brasileiros de oftalmologia Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO |
| ISSN: | 0004-5578 |
| Popis: | WOS: 000455788400003 PubMed: 30652762 Purpose:Obesity is associated with eye diseases, but the underlying structural changes and pathogenic mechanisms have not been examined in detail. Here, we assessed the effects of morbid obesity on the morphometric indices of eye disease. Methods: Morbidly obese volunteers (n=101, body mass index [BMI] >= 40) and healthy individuals (n=95, BMI: 18.50-24.99) were examined by Goldman applanation tonometry, pachymetry, and spectral domain optical coherence tomography. Intraocular pressure, anterior chamber depth, axial length, central corneal thickness, retinal nerve fiber layer thickness, central fovea! thickness, and choroidal thickness were compared between groups. Results: Uncorrected intraocular pressure was significantly greater in the morbidly obese group than in the healthy control group (15.5 +/- 2.5 vs. 14.5 +/- 2.6 mmHg, p=0.009), whereas axial length, anterior chamber depth, and central corneal thickness did not differ between the groups. The mean retinal nerve fiber layer thickness at the temporal quadrant was reduced in the morbidly obese group (72.7 +/- 13.6 vs. 85.05 +/- 52.6 mu m, p=0.024). Similarly, the mean retinal thicknesses at nasal and temporal 1500-mu m locations were lower in the morbidly obese group (346.6 +/- 18.2 vs. 353.7 +/- 18.8 mu m, p=0.008; 323.1 +/- 20.3 vs. 330.0 +/- 18.9 mu m, p=0.001). The mean choroidal thickness was also reduced in almost all measurement locations (fovea, temporal 500 and 1000 mu m, and nasal 500, 1000, and 1500 mu m) of the obese group (p |
| Databáze: | OpenAIRE |
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