Tooth loss as a risk factor for dementia: systematic review and meta-analysis of 21 observational studies
| Autor: | Beibei Gu, Ying-mei Wei, Yi Li, Songhua Xiao, Shaowei Liao, Ying Xiong, Mujun Jiang, Wang Liao, Shengnuo Fan, Yuqiu Zheng, Wenli Fang, Jun Liu |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty lcsh:RC435-571 Tooth loss Odds 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine lcsh:Psychiatry medicine Odds Ratio Dementia Humans 030212 general & internal medicine Risk factor Risk assessment Aged business.industry Incidence (epidemiology) Incidence 030206 dentistry Middle Aged medicine.disease Psychiatry and Mental health Meta-analysis Observational Studies as Topic Cognitive impairment Regression Analysis Observational study Female medicine.symptom business Research Article |
| Zdroj: | BMC Psychiatry BMC Psychiatry, Vol 18, Iss 1, Pp 1-11 (2018) |
| ISSN: | 1471-244X |
| Popis: | Background Tooth loss is suggested to be associated with an increased risk of dementia in many studies. But the relationship between tooth loss and dementia is not yet fully understood. This systematic review and meta-analysis aimed to determine the relative effect of tooth loss on dementia risk. Methods An electronic search of PubMed, Scopus, Embase, and Web of Knowledge was conducted in March 2018 to identify relevant observational studies with the English language restriction. Studies were included if they assessed the relationship between tooth loss and risk of dementia. Study quality was detected by the modified Downs and Black scale. Odds risks (ORs) were pooled using a random-effects model in the crude model. Results The literature search initially yielded 1574 articles, and 21 observational studies published between 1994 and 2017 were finally included for the analyses. The crude results with random-effects model showed that patients with multiple tooth loss had higher incidence of dementia (OR 2.62, 95% CI 1.90–3.61, P |
| Databáze: | OpenAIRE |
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