Dermal Equivalents in Oncology: Benefit of One-Stage Procedure
| Autor: | Yves Tropet, Anne Grumblat, Arnaud Fotso, Ahmed Elkhyat, Philippe Humbert, Sophie Mac, Julien Pauchot, Gwenaël Rolin |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Oncology medicine.medical_specialty Skin Neoplasms Time Factors Adolescent Dermatology Surgical Flaps Young Adult Equivalent Internal medicine medicine Humans Surgical Wound Infection Aged Retrospective Studies Dermal equivalent Aged 80 and over Skin Artificial Wound Healing integumentary system business.industry Chondroitin Sulfates One stage Retrospective cohort study Skin Transplantation General Medicine Middle Aged Plastic Surgery Procedures Skin transplantation Infection rate Elastin Surgery Otorhinolaryngologic Neoplasms Head and Neck Neoplasms Collagen business Wound healing |
| Zdroj: | Dermatologic Surgery. 39:43-50 |
| ISSN: | 1076-0512 |
| Popis: | BACKGROUND In oncology, dermal equivalent may be indicated to cover losses of substance related to skintumors or after the removal of skin flaps.OBJECTIVE To report our experience of two dermal equivalents, Matriderm 1 mm with a one-stage graft(DE1) and Integra DL with a two-stage graft (DE2) in oncology.PATIENTS AND METHOD Retrospective, single-center study involving 16 patients.RESULTS Sixteen patients received dermal equivalents as an alternative to flaps (7 cases), over tendinousareas (7 cases), and for cosmetic purposes (2 cases). Twelve patients received DE1 and four DE2. Woundhealing times with DE1 were 4 weeks less than those with DE2. Three cases of infection were noted with DE2.The use of dermal equivalents as an alternative to skin flaps was effective, and no adhesions were found overthe tendinous areas.CONCLUSION The learning curve, the two-stage graft required with DE2, and not using a vacuum-assistedclosure system can explain the high infection rate. The use of dermal equivalents is particularly indicated inthe treatment of skin defect in oncology. The possibility of a one-stage graft with DE1 and combination withnegative pressure therapy is beneficial.The authors have indicated no significant interest with commercial supporters. |
| Databáze: | OpenAIRE |
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