Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits

Autor: Pedro Carriquiriborde, R. Foti, M. Rojo, Diana Álvarez-Muñoz, Sara Rodríguez-Mozaz, Alejandro Arturo Dománico, Damià Barceló
Přispěvatelé: Ministerio de Economía y Competitividad (España), Álvarez-Muñoz, Diana, Barceló, Damià, Álvarez-Muñoz, Diana [0000-0002-1891-3233], Barceló, Damià [0000-0002-8873-0491]
Rok vydání: 2019
Předmět:
Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
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ISSN: 0269-7491
DOI: 10.1016/j.envpol.2019.05.099
Popis: The accumulation of 17 human pharmaceuticals (HPs) was investigated in the muscle of three fish species characteristic of the “Rio de la Plata Basin” with different feeding habits and of relevance for human consumption: Megaleporinus obtusidens, Salminus brasiliensis, and Prochilodus lineatus. Fish were sampled in fall and spring from 8 localities distributed along 500 Km of the Uruguay River. Atenolol and carbamazepine were the most frequently detected HPs (>50%), but at concentrations always below 1 μg/kg wet weight (w/w). Hydrochlorothiazide, metoprolol, venlafaxine, propranolol, codeine, and the carbamazepine metabolite, 2-hydroxycarbamazepine, were accumulated at higher levels showing maximum concentrations between 1 and 10 μg/kg (w/w), but infrequently (
Macarena Rojo, the sampling and partially the sample analysis were granted by the Fish and Fisheries Program of the Administrative Commission of the Uruguay River (CARU). The study was also granted by CONICET (PIP2012-2014-0090) and ANPCyT (PICT2014-1690). The scientific facilities of ICRA have been co-financed by the Spanish Ministry of Economy and Competitiveness (MINECO) and by the European Regional Development Fund (ERDF) in the frame of the Catalonia ERDF Operative programme 2007–2013. This work was partly supported by the Generalitat de Catalunya (Consolidated Research Group: Catalan Institute for Water Research 2014 SGR 291). S. Rodriguez-Mozaz also acknowledges the Ramon y Cajal program (RYC-2014-16707) and. Diana Álvarez-Muñoz the support of the project XENOMETABOLOMIC (CTM2015-73179-JIN) (AEI/FEDER/UE).
Databáze: OpenAIRE