Cloprostenol administration in the first week postpartum reduces expression of oxytocin receptors in the endometrium in Holstein-Zebu cows

Autor: João Carlos Pinheiro Ferreira, Aline Sousa Camargos, Eunice Oba, S. Wohlres-Viana, Luiz Sérgio de Almeida Camargo, Alcides de Amorim Ramos, I. F. Costa
Přispěvatelé: Instituto Federal Goiano - IF Goiano, Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA), Universidade Estadual Paulista (Unesp), A.Camargos, IF Goiano, S. Wohlres-Viana, I. F. Costa, Universidade Estadual Paulista, LUIZ SERGIO DE ALMEIDA CAMARGO, CNPGL, J. C. Ferreira, Universidade Estadual Paulista, Universidade Estadual Paulista, E. Oba, Universidade Estadual Paulista.
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.69 n.4 2017
Arquivo brasileiro de medicina veterinária e zootecnia
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Volume: 69, Issue: 4, Pages: 821-829, Published: AUG 2017
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol 69, Iss 4, Pp 821-829
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Popis: The present study investigated the hormonal profile and expression of prostaglandin F2? (PGF2?), oxytocin and estrogen receptors in uterine tissues of postpartum cows treated with cloprostenol. Twenty HolsteinZebu crossbred cows were treated with saline solution (treatment CONT) or cloprostenol (treatment CLO), both administered two and five days postpartum. Blood samples were collected on days two, seven, 14, 21 and 28 postpartum for progesterone, PGF2? metabolite (PGFM) and estradiol determination, and endometrial biopsy was performed in order to quantify the expression of oxytocin receptor (OXTR), prostaglandin F receptor (PTGFR) and estrogen receptor 1 (ERS1) genes. In the CLO treatment, expression of OXTR was reduced (P0.05) between treatments was found for PTGFR and ERS1 expression. Estrogen concentrations increased progressively until day 14 (P0,05). Os níveis de PGFM foram altos durante todo o estudo. Conclui-se que a administração de cloprostenol nos dias dois e cinco pós-parto parece diminuir a expressão de OXTR no endométrio em vacas mestiças. Made available in DSpace on 2018-01-23T16:05:09Z (GMT). No. of bitstreams: 1 Cnpgl2017ArqBrasMVZCamargosCloprostenol.pdf: 300195 bytes, checksum: 678730be01dcaefeb5d2883455f2b8ed (MD5) Previous issue date: 2018-01-17
Databáze: OpenAIRE