Cloprostenol administration in the first week postpartum reduces expression of oxytocin receptors in the endometrium in Holstein-Zebu cows
Autor: | João Carlos Pinheiro Ferreira, Aline Sousa Camargos, Eunice Oba, S. Wohlres-Viana, Luiz Sérgio de Almeida Camargo, Alcides de Amorim Ramos, I. F. Costa |
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Přispěvatelé: | Instituto Federal Goiano - IF Goiano, Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA), Universidade Estadual Paulista (Unesp), A.Camargos, IF Goiano, S. Wohlres-Viana, I. F. Costa, Universidade Estadual Paulista, LUIZ SERGIO DE ALMEIDA CAMARGO, CNPGL, J. C. Ferreira, Universidade Estadual Paulista, Universidade Estadual Paulista, E. Oba, Universidade Estadual Paulista. |
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Prostaglandin F receptor
medicine.medical_specialty 040301 veterinary sciences medicine.drug_class RT-PCR progesterone Prostaglandin Estrogen receptor Endometrium progesterona 0403 veterinary science Andrology chemistry.chemical_compound estradiol medicine PTGFR ESRI lcsh:SF1-1100 General Veterinary medicine.diagnostic_test business.industry Obstetrics ESR1 0402 animal and dairy science 04 agricultural and veterinary sciences Estradiol 040201 dairy & animal science Oxytocin receptor medicine.anatomical_structure chemistry Oxytocin Estrogen lcsh:Animal culture business medicine.drug Endometrial biopsy |
Zdroj: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.69 n.4 2017 Arquivo brasileiro de medicina veterinária e zootecnia Universidade Federal de Minas Gerais (UFMG) instacron:UFMG Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Volume: 69, Issue: 4, Pages: 821-829, Published: AUG 2017 Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol 69, Iss 4, Pp 821-829 Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice) Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA |
Popis: | The present study investigated the hormonal profile and expression of prostaglandin F2? (PGF2?), oxytocin and estrogen receptors in uterine tissues of postpartum cows treated with cloprostenol. Twenty HolsteinZebu crossbred cows were treated with saline solution (treatment CONT) or cloprostenol (treatment CLO), both administered two and five days postpartum. Blood samples were collected on days two, seven, 14, 21 and 28 postpartum for progesterone, PGF2? metabolite (PGFM) and estradiol determination, and endometrial biopsy was performed in order to quantify the expression of oxytocin receptor (OXTR), prostaglandin F receptor (PTGFR) and estrogen receptor 1 (ERS1) genes. In the CLO treatment, expression of OXTR was reduced (P0.05) between treatments was found for PTGFR and ERS1 expression. Estrogen concentrations increased progressively until day 14 (P0,05). Os níveis de PGFM foram altos durante todo o estudo. Conclui-se que a administração de cloprostenol nos dias dois e cinco pós-parto parece diminuir a expressão de OXTR no endométrio em vacas mestiças. Made available in DSpace on 2018-01-23T16:05:09Z (GMT). No. of bitstreams: 1 Cnpgl2017ArqBrasMVZCamargosCloprostenol.pdf: 300195 bytes, checksum: 678730be01dcaefeb5d2883455f2b8ed (MD5) Previous issue date: 2018-01-17 |
Databáze: | OpenAIRE |
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