Patterns of Care and Efficacy of Chemotherapy and Radiotherapy in Skin-Involved Breast Cancers of All Sizes
| Autor: | Allison A. Aggon, Elias Obeid, Shelly B. Hayes, Lyudmila DeMora, Richard J. Bleicher, Anna M. Mazor, Elin R. Sigurdson, John M. Daly, Elizabeth Handorf, Alina M. Mateo |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
0301 basic medicine Oncology Cancer Research medicine.medical_specialty Skin Neoplasms Adolescent Receptor ErbB-2 medicine.medical_treatment Breast Neoplasms Systemic therapy Article Young Adult 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine medicine Overall survival Humans Practice Patterns Physicians' Stage (cooking) Aged Retrospective Studies Aged 80 and over Patterns of care Chemotherapy business.industry Chemoradiotherapy Middle Aged Patient Acceptance of Health Care Prognosis medicine.disease Neoadjuvant Therapy Cancer data Survival Rate Radiation therapy 030104 developmental biology Receptors Estrogen 030220 oncology & carcinogenesis Female Receptors Progesterone business Follow-Up Studies |
| Zdroj: | Clin Breast Cancer |
| ISSN: | 1526-8209 |
| DOI: | 10.1016/j.clbc.2019.02.003 |
| Popis: | BACKGROUND: The management of small skin-involved (SI) invasive breast cancers is controversial because, although considered “unresectable,” prior data shows that their prognosis is far better than their Stage III classification. This study was undertaken to determine how SI lesions are treated in the United States, and to discern the benefit of systemic therapy. METHODS: Patients diagnosed with stage I-III breast cancer in the National Cancer Database between 2004 and 2011 were reviewed. Treatment patterns were examined and overall survival (OS) was assessed. RESULTS: 3,485 patients had SI and 456,287 patients had non-SI breast cancers. Chemotherapy was administered to 68.5% of SI and 45.9% of non-SI tumors (p |
| Databáze: | OpenAIRE |
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