The effect of drugs on serum histidine levels in rheumatoid arthritis
| Autor: | N. G. Sitton, M. E. Pickup, K. E. Surrall, J S Dixon, M.F.R. Martin, Howard A. Bird |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Male
medicine.medical_specialty Captopril Immunology Anti-Inflammatory Agents chemistry.chemical_element Arthritis Zinc Trientine Arthritis Rheumatoid Grip strength Rheumatology Internal medicine Humans Immunology and Allergy Medicine Histidine Clofibrate Sulfates business.industry Penicillamine Hydroxychloroquine Middle Aged medicine.disease Zinc Sulfate Drug Combinations Endocrinology chemistry Rheumatoid arthritis Female business medicine.drug |
| Zdroj: | Rheumatology International. 3:145-149 |
| ISSN: | 1437-160X 0172-8172 |
| DOI: | 10.1007/bf00541592 |
| Popis: | Groups of 15 patients with active rheumatoid arthritis were treated for 24 weeks with zinc sulphate, trien, captopril, clozic in two doses or a combination of D-penicillamine and hydroxychloroquine. Serum histidine levels were monitored along with measures of disease activity including C-reactive protein, plasma viscosity, articular index, grip strength and early morning stiffness. Zinc sulphate and trien were found to be ineffective while the other drugs all showed evidence of second-line action. Serum histidine was found to improve during successful therapy. The possible cause of low serum histidine and its response to therapy is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink