Prognostic factors for survival and tumor control in cervical lymph node metastases from head and neck cancer: A multivariate study of 492 cases
| Autor: | Isabel Millán, Jose Otero, L. Cerezo, Alejandro de la Torre, G. Aragón |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Oncology Cancer Research medicine.medical_specialty Multivariate analysis Adolescent medicine.medical_treatment Internal medicine medicine Humans Child Lymph node Aged Neoplasm Staging Retrospective Studies Fixation (histology) Aged 80 and over business.industry Head and neck cancer Middle Aged Prognosis medicine.disease Combined Modality Therapy Survival Analysis Primary tumor Surgery Radiation therapy medicine.anatomical_structure Lymphatic system Head and Neck Neoplasms Child Preschool Lymphatic Metastasis Multivariate Analysis Carcinoma Squamous Cell Female Neoplasm Recurrence Local business Complication Neck Follow-Up Studies |
| Zdroj: | Europe PubMed Central |
| ISSN: | 0008-543X |
| Popis: | A multivariate analysis was carried out in 492 patients with metastatic neck disease from squamous cell carcinoma to determine the influence of clinical and therapeutic factors on survival, local and regional control, and distant metastases. After radiation treatment with radical intent, recurrence at the primary site was the most frequent site of treatment failure (20% of cases), followed by distant metastases (14% of the cases), whereas isolated neck recurrences occurred in only 7% of the patients. The most significant factors influencing survival were primary tumor site, node fixation, N-stage, T-stage, and number of lymphatic chains. The most significant factors influencing local control were primary site, T-stage, and node fixation. Significant factors influencing regional control were radiation therapy volume, primary tumor site, node fixation, and node location (upper and lower neck). Significant factors influencing distant control were N-stage, number of nodes, and number of involved lymphatic chains. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text