Comparison of Two Routes of Administration of Dexamethasone to Reduce the Postoperative Sequelae After Third Molar Surgery: A Systematic Review and Meta-Analysis
| Autor: | Luigi Laino, Cesare D’Amico, Khrystyna Zhurakivska, Lorenzo Lo Muzio, Marco Cicciù, Giuseppe Troiano, Luca Fiorillo, Gabriele Cervino |
|---|---|
| Přispěvatelé: | Troiano, Giuseppe, Laino, Luigi, Cicciù, Marco, Cervino, Gabriele, Fiorillo, Luca, D’Amico, Cesare, Zhurakivska, Khrystyna, Muzio, Lorenzo Lo |
| Rok vydání: | 2017 |
| Předmět: |
Molar
medicine.medical_specialty Wisdom tooth Trismus law.invention Postoperative pain 03 medical and health sciences 0302 clinical medicine Oral surgery Randomized controlled trial law Third molar Medicine Corticosteroid Corticosteroids Edema 030212 general & internal medicine General Dentistry Dexamethasone Trismu business.industry 030206 dentistry Surgery Clinical trial medicine.anatomical_structure Meta-analysis Dentistry medicine.symptom business Intramuscular injection medicine.drug |
| Zdroj: | The Open Dentistry Journal |
| ISSN: | 1874-2106 |
| Popis: | The aim of this systematic review and meta-analysis was to compare the clinical efficacy of two routes of dexamethasone administration in reducing the postoperative sequelae after third molar extraction. Electronic databases (PUBMED, SCOPUS and EBSCO library) were screened in order to find both randomized and non-randomized clinical trials that directly compare the submucosal intraoral or the intramuscular extraoral administration of dexamethasone. No restriction about year of publication was imposed. About 340 titles and abstracts were screened independently by two authors. Of these [340 titles], only 4 randomized clinical trials met the inclusion criteria and were included in the meta-analysis. No statistical differences in postoperative pain, swelling and trismus were recorded comparing the intraoral submucosal and the extraoral intramuscular injection of dexamethasone in an extraoral site. The aim of this systematic review and meta-analysis was to compare the clinical efficacy of two routes of dexamethasone administration in reducing the postoperative sequelae after third molar extraction. Electronic databases (PUBMED, SCOPUS and EBSCO library) were screened in order to find both randomized and non-randomized clinical trials that directly compare the submucosal intraoral or the intramuscular extraoral administration of dexamethasone. No restriction about year of publication was imposed. About 340 titles and abstracts were screened independently by two authors. Of these [340 titles], only 4 randomized clinical trials met the inclusion criteria and were included in the meta-analysis. No statistical differences in postoperative pain, swelling and trismus were recorded comparing the intraoral submucosal and the extraoral intramuscular injection of dexamethasone in an extraoral site. |
| Databáze: | OpenAIRE |
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